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doi: 10.1074/jbc.M111053200 20 LambertAJBuckinghamJABoysenHMBrandMD

Comput Struct Biotechnol J

Think of it as a metabolic switch

En ese marco, los derivados de quinolinio como 5-Amino-1MQ (5-amino-1-metilquinolinio) emergieron como inhibidores de molcula pequea capaces de bloquear la metilacin de nicotinamida sin las limitaciones de biodisponibilidad de agentes de mayor tamao